Invited Faculty
  • Marina Botto
    Imperial College London
    UK
  • Marina Botto is Professor of Rheumatology, Head of the Department of Immunology and Inflammation and Director of Bioservices at Imperial College London. She is also an Honorary Consultant Rheumatologist at Imperial Academic Health Science Centre.

    Professor Botto received her medical degree and qualification in Rheumatology in Italy. She then moved to the UK where she completed her academic training. She is a member of the American College of Rheumatology. In 2009 she was elected Fellow of the UK Academy of Medical Sciences. She has authored over 200 original publications on the complement system and the pathogenesis of systemic lupus erythematosus (SLE). She is a member and/or Chair of several grant committees in the UK and in Europe.

    Professor Botto research focuses on complement biology and systemic autoimmunity. Over the years she has developed several animal models of complement deficiency that have helped to understand the role of complement in SLE, renal diseases and more recently in cancer and metabolism. She has also pioneered the idea that the complement component C1q can act outside the complement system and has roles in ageing, angiogenesis, cancer and immunometabolism. Her work, using a variety of experimental models has opened the way to the design of targeted complement inhibitor strategies that will have the potential to treat individuals suffering from a wide range of chronic inflammatory conditions. She has supervised more than 40 students.
    Research & Clinical Focus

    Systemic lupus erythematosus (SLE)

    Complement Biology

    Mouse Models

    Immunometabolism

    T-Cells

    • Date Time Room Session Title Lecture Title
    May 18 17:20-17:40 Room Grand Ballroom 101 [Concurrent Session 4] Cytokines and Cell Signaling Type I IFN and T cell metabolism in SLE